Ira Bergman

Ira Bergman

Contact

Office: Children's Hospital, Dept. of Pediatrics and Neurology

Lab: 3505 Rangos Research Building

Pittsburgh, PA 15224

Ph: 412 692-7176

Fax: 412-692-6787

bergman@pitt.edu

Website »

Education

  • BA, Yale University
  • MD, University of Chicago
  • PhD, University of Pittsburgh

Academic Affiliation

  • Professor of Pediatrics, Neurology and Immunology

Selected Publications

1. Bergman I, Barmada MA, Heller G, Griffin JA, Cheung NKV: Treatment of neoplastic meningeal xenografts by intraventricular administration of an antiganglioside monoclonal antibody, 3F8. Int J Cancer 1999;82:538-548. PMID: 10404068

2. Bergman I, Barmada MA, Griffin JA, Slamon, DJ: Treatment of meningeal breast cancer xenografts in the rat with an anti-p185/Her2 antibody. Clinical Cancer Research, 2001;7:2050-6. PMID: 11448923

3. Bergman I, Whitaker-Dowling P, Gao Y, Griffin JA: Preferential targeting of Vesicular Stomatitis Virus to breast cancer cells. Virology, 2004; 330: 24-33. PMID: 15527831

4. Bergman I, Griffin JA, Gao Y, Whitaker-Dowling P: Treatment of implanted mammary tumors with recombinant vesicular stomatitis virus targeted to Her2/neu. International Journal of Cancer, 2007; 121: 425-30. PMID: 17354238

5. Gao Y, Whitaker-Dowling P, Griffin JA, Barmada MA, Bergman I: Recombinant vesicular stomatitis virus targeted to Her2/neu combined with anti-CTLA4 antibody eliminates implanted mammary tumors. Cancer Gene Therapy, 2009; 16: 44-52. PMID: 18654610

6. Gao Y, Whitaker-Dowling P, Griffin JA, Bergman I: Treatment with targeted Vesicular Stomatitis Virus generates therapeutic multifunctional anti-tumor memory CD4. Cancer Gene Therapy, 2012; 19: 282-91. PMID: 22240921

7. Gao Y, Whitaker-Dowling P, Bergman I:  Memory anti-tumor T-cells resist inhibition by immune suppressor cells.  Anticancer Research 2015: 35: 4593-97. PMID:26254347

8. Gao Y, Barmada MA, Bergman I:  Antitumor Memory T-Cells Become Functionally Mature from 30 to 100 days in a Mouse Model of Neoplasia.  Anticancer Research 2018:38:147-157.  PMID: 29277767

9. Gao Y, Bergman I:  Potent Antitumor T-Cell Memory Is Generated by Curative Viral Oncolytic Immunotherapy But Not Curative Chemotherapy.  Anticancer Research 2018:38:6621-29.  PMID: 30504370

Research Interests

  • Viral immunotherapy of cancer metastases
  • Viral immunotherapy to prevent cancer metastases