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Regulatory T cells are heterogenous in the tumor microenvironment
Regulatory T cells are heterogenous in the tumor microenvironment
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Fungal Immunology
Gaffen Lab: pSTAT3 in basal epithelial layer during oropharyngeal candidiasis (Green= Keratin, Red= pSTAT3, Blue= DAPI)
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Immune regulation in tumors
Vignali Lab: Immune Infiltrates in Breast Cancer (CD20- cyan, CD4- green, CD8- orange, CD68- red, Foxp3- yellow, PanCK- magenta, DAPI- blue)
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Intestinal Organoids
Meisel Lab: Gut in a Dish
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Protein capture in lymph nodes
Binder Lab: Intradermal immunization with gp96 leads to its localization in CD11b+CD11c+ cells in the draining lymph node.
Mission
The mission of the Department of Immunology is to discover new mechanisms and pathways of the immune system to enrich human health by combating and preventing disease, enhancing vaccination, and controlling autoimmunity. The department has a mission of training students, post-doctoral fellows, physicians, and other young scientists to be proficient in immunology.
![Global Impact](/sites/default/files/styles/single_image_highlight/public/block-img/salk%20vaccine%20image.jpg?itok=Sb3zn5lT)
Global Impact
From Jonas Salk's discovery of the polio vaccine in the 1950s to ongoing research on immune system mechanisms and pathways, Pitt immunologists have profoundly improved human health.