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Ask an Immunologist

Ask an Immunologist: How Does a Tattoo Impact the Immune System?

August 26, 2026 | By Lexi Bowman

The meaning behind a tattoo is permanent. However, the vibrant colors are not. Immune cells called macrophages are responsible both for causing ink to fade over time and allowing it to be seen in the first place. New research also suggests that these processes could have consequences for immune function, but much more research is needed.